Once the HIPAA Enrollment Master is installed, you can launch it from the "Start" menu:
Start 
Programs (All Programs) HIPAASuite HIPAA Enrollment Master HIPAA Enrollment Master.
The HIPAA Enrollment Master is launched from the "Start" menu
The following screen will appear:
The HIPAA Enrollment Master main window
Once the main program window is opened, the normal operation now would be to open an EDI file or a folder. See: